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Updated: Jun 26, 2025

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对新型Enterococcus faecalis菌体的洞察:一个全面的基因组分析

Sahar Abed1,2, Mohammad Sholeh2, Mahshid Khazani Asforooshani2

  • 1Department of Microbial Biotechnology, Faculty of Basic Sciences and Advanced Technologies in Biology, University of Science and Culture, Tehran, Iran.

PloS one
|May 14, 2024
PubMed
概括

使用菌体SAM-E.f 12的菌体疗法显示出对抗生素耐药性Enterococcus faecalis. 12的治疗有希望. 这项研究详细介绍了其基因组分析和在小鼠伤口模型中的有效性,为抗生素提供了有针对性的替代品.

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Lysogenic Cycle of Bacteriophages

In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
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