增长分化因子-5 + 104T>C多态与膝盖,手和关节骨关节炎风险的相关性:基于47项病例控制研究的病例控制研究和元分析

Kamran Alijanpour1, Seyed Alireza Dastgheib2, Leila Azizi3

  • 1General Practitioner, Babol University of Medical Sciences, Babol, Iran.

概括

增长差异化因子5 (GDF-5) +104T>C多态性在全球范围内提供了防止骨关节炎 (OA) 发展的保护. 这种遗传变异有利于高加索,亚洲和非洲人群,降低膝盖和手部OA的风险,但不是部OA.

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