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Osr2作为一种生物机械检查点,在瘤中加剧CD8+T细胞耗尽

Jinjia Zhang1, Junhong Li1, Yongqiang Hou1

  • 1State Key Laboratory of Cellular Stress Biology, Xiang'an Hospital, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China.

Cell
|May 14, 2024
PubMed
概括

转录因子 Osr2 集成机械信号以驱动瘤特异性的 CD8+ T 细胞耗尽. 向Osr2可以通过恢复T细胞功能来增强癌症免疫疗法.

关键词:
标签: 美国皮埃佐1T细胞耗尽生物机械应力癌症免疫疗法

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