发现口腔癌预后因素排名使用协会规则采矿
Sitthi Chaowchuen1, Kritsasith Warin2, Rachasak Somyanonthanakul3
1Udonthani Cancer Hospital, Muang Udonthani, Udonthani, Thailand.
European journal of dentistry
|May 14, 2024
概括
外节延伸和神经/淋巴系统的侵入是影响口腔癌存活率的关键因素. 识别这些预后指标可以提高对口腔癌预后和生存率的理解.
科学领域:
- 在瘤学瘤学.
- 数据挖掘 数据挖掘
背景情况:
- 口腔癌预后评估依赖于5年生存率.
- 确定关键的预后因素对于改善患者的治疗结果至关重要.
研究的目的:
- 使用关联规则挖掘 (ARM) 分析口腔癌数据.
- 发现和排名影响口腔癌5年生存率的预后因素.
主要方法:
- 897名口腔癌患者 (2011-2017年) 的回顾性分析.
- 应用多变量考克斯比例危险分析和ARM.
- 对临床病理学和治疗数据的评估.
主要成果:
- 五年整体生存率为35.1%.
- 显著的预后因素包括瘤阶段,淋巴结转移,手术边缘,外节延伸,复发和远程转移.
- 5年死亡率的最高预测因素是正极管外延伸,围神经入侵和淋巴血管入侵.
结论:
- 外节延伸,围神经入侵和淋巴血管入侵是口腔癌5年生存率的主要预后因素.
- 这些因素显著影响到五年内死亡的可能性.
- ARM有效地对口腔癌预后的这些关键指标进行了排名.
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