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Updated: Jun 26, 2025

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
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H2A.Z护航者聚集在黑色素瘤细胞增殖的E2F点基因上

Sina Jostes1,2,3, Chiara Vardabasso1,2, Joanna Dong1,2

  • 1Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

Genes & development
|May 14, 2024
PubMed
概括

高的H2A.Z水平驱动黑色素瘤的生长. 针对其伴侣SRCAP,P400和YL1,影响细胞周期基因和H4乙化,为黑色素瘤治疗提供新的表观遗传策略.

关键词:
在H2A.Z.表观遗传学是指表观遗传学.希斯辅导者 希斯辅导者基因组变异的基因组变异黑色素瘤是一种黑色素瘤.

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