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Updated: Jun 26, 2025

RNAi Trigger Delivery into Anopheles gambiae Pupae
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Published on: March 8, 2016

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通过dsRNAi介导的PIAS2beta的沉默,通过线粒体灾难,专门杀死了亚塑性癌瘤

Joana S Rodrigues1,2, Miguel Chenlo1, Susana B Bravo3

  • 1Neoplasia & Endocrine Differentiation, Centro de Investigación en Medicina Molecular y Enfermedades Crónicas (CIMUS), University of Santiago de Compostela (USC), Instituto de Investigación Sanitaria (IDIS), Santiago de Compostela, Spain.

Nature communications
|May 14, 2024
PubMed
概括

通过RNA干扰向PIAS2β抑制了对抗性甲状腺癌 (ATC) 的生长. 这种PIAS2b-dsRNAi疗法对ATC和其他侵袭性形性癌症有前途.

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