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Updated: Jun 26, 2025

Generation of Orthotopic Pancreatic Tumors and Ex vivo Characterization of Tumor-Infiltrating T Cell Cytotoxicity
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解读PGRN在调节CD8+ T细胞抗瘤免疫力中的潜在作用

Wenyu Zhang1,2, Huan Qin1,2, Guosheng Wang1,2

  • 1Department of Pulmonary and Critical Care Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.

Cell death discovery
|May 14, 2024
PubMed
概括

进激素 (PGRN) 是一种新的标,用于增强肺癌中CD8+T细胞抗瘤免疫力. 缺少PGRN可以增强T细胞活性,克服对免疫检查点阻塞 (ICB) 疗法的抵抗力.

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