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Updated: Jun 26, 2025

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在真菌细菌中向蛋白质降解揭示了抗菌作用,并增强了抗生素的疗效

Harim I Won1, Samuel Zinga1, Olga Kandror1

  • 1Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.

Nature communications
|May 14, 2024
PubMed
概括

向蛋白解酶的仿真体 (PROTACs) 提供了一种降解疾病蛋白质的新方法. 这项研究确定了PROTACs的细菌蛋白点,显示了新的结核病抗生素的潜力.

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Defense Against Bacterial Pathogens

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Overview
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RNA...
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Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
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Regulated Protein Degradation

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