预防PICS的非药物干预措施在重症成人患者:一个系统审查和网络元分析的协议
Xiaoying Sun1,2, Qian Tao2, Qing Cui3
1School of Nursing, Sun Yat-Sen University, Guangzhou, 510080, China.
后重症监护综合征 (PICS) 影响了许多ICU患者. 本研究系统地审查非药物干预措施,以找到PICS最有效的预防策略,改善患者的治疗结果.
科学领域:
- 临界护理医学 临界护理医学
- 基于证据的实践.
- 系统审查方法论 系统审查方法论
背景情况:
- 后重症监护综合征 (PICS) 是一种流行病,在重症监护单元 (ICU) 入院后影响严重病情的成年患者.
- 目前对预防PICS的非药理学措施进行的比较分析缺乏关于最佳治疗疗效的全面证据.
- 对于指导PICS预防临床实践的强有力的证据的需求至关重要.
研究的目的:
- 系统地审查和综合有关预防后重症监护综合征 (PICS) 的非药物干预的证据.
- 进行贝叶斯网络元分析 (NMA) 来比较各种非药物干预措施的有效性,并将其与通常的护理进行比较.
- 确定成人ICU患者PICS预防的最有效的非药理学策略.
主要方法:
- 在9个电子数据库中系统搜索关于非药物预防PICS的随机对照试验 (RCT).
- 数据提取和偏差风险评估,使用两位独立审查员的Cochrane协作工具.
- 应用传统的对对元分析和贝叶斯的NMA来评估干预的有效性,使用NMA工具的信心评估的信心.
主要成果:
- 为了预防PICS存在多种非药理干预措施,但直接比较数据有限.
- 大多数干预措施只与标准护理进行了比较,这阻碍了对相对有效性的清晰理解.
- 该研究旨在提供各种PICS预防策略的比较有效性数据.
结论:
- 目前关于非药物干预措施对PICS预防的比较有效性的证据不足.
- 这一系统性审查和NMA将为PICS预防的最佳非药物战略提供有价值的见解.
- 研究结果将为医疗保健提供者和指导方针制定者在为成人ICU患者选择有效的PICS预防干预措施方面提供信息.
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