更年期妇女的母乳养时间和糖尿病之间的关联:使用基于人口的回顾性研究进行机器学习分析
Eun-Saem Choi1, Jue Seong Lee2, Hwasun Lee3
1Department of Obstetrics & Gynecology, Korea University College of Medicine, Korea University Anam Hospital, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Korea.
International breastfeeding journal
|May 15, 2024
概括
长达12个月的母乳养与患糖尿病 (DM) 的风险较低有关. 与那些母乳养不到12个月的妇女相比,没有母乳养的妇女患DM的风险明显增加.
科学领域:
- 内分泌学 在内分泌学.
- 生殖健康 生殖健康
- 公共卫生 公共卫生
背景情况:
- 母乳养会影响怀孕后的胰岛素抵抗,但它与糖尿病 (DM) 的联系仍在争论中.
- 以前的研究表明,关于母乳养时间和DM风险的结果不一致.
研究的目的:
- 在大量人群中调查母乳养时间与患DM的风险之间的关联.
- 开发机器学习模型,根据母乳养时间来预测DM和HbA1c水平.
主要方法:
- 使用了韩国国家健康和营养检查调查数据库 (2010-2020).
- 包括15946名绝经后妇女,按母乳养时间分类:没有,<12个月和≥12个月.
- 开发了使用各种机器学习算法的预测模型 (ANN,决策树,后勤回归,Naïve Bayes,随机森林,SVM).
主要成果:
- 在12个月以下的母乳养组中,DM患病率最低 (9.0%).
- 不母乳养的妇女 (10.4%) 和母乳养≥12个月的妇女 (16.7%) 的DM患病率更高.
- 调整后的分析显示,在没有母乳养 (aOR 1.29) 和≥12个月母乳养 (aOR 1.18) 的情况下,DM风险增加,而在<12个月的情况中,DM风险增加.
- 在DM和HbA1c预测模型中,母乳养时间是显著的预测因素.
结论:
- 不母乳养与患上糖尿病的风险更高有关.
- 长达12个月的母乳养似乎可以防止绝经后妇女发展DM.
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