支气管镜检查期间呼吸道出血中的内支气管烯不引起高血压:一项回顾性观察性研究
Jeremy Kim1, Chinh Phan1, Jason Adams1,2
1Department of Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of California, Davis School of Medicine.
Journal of bronchology & interventional pulmonology
|May 15, 2024
概括
在支气管镜检查期间,与冷盐水相比,内支气管内烯酸并没有显著改变全身血压. 这表明基是控制气道出血的安全替代品.
科学领域:
- 肺部病理学 肺部病理学
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 支气管镜检查可以导致气道出血,特别是在侵入性手术中.
- 烯是一种血管收缩剂,是一种潜在的局部治疗呼吸道出血的方法.
- 末支腺的系统性作用需要进一步评估.
研究的目的:
- 为了比较 Endobronchial phenylephrine 与冷盐溶液在支气管镜检查期间对全身血压的影响.
主要方法:
- 对160名经过支气管镜检查的患者进行了回顾性观察性研究.
- 患者接受了内支气管内烯酸或冷盐水.
- 测量和比较了各组之间的手术内血压变化.
主要成果:
- 利弗林和冷盐水组之间没有观察到静脉缩,腹缩或平均动脉血压变化的统计学上显著差异.
- 绝对静脉血压变化的中位数为31.8mmHg (非) 和29mmHg (冷盐水).
- 系统血压变化的中位数为28% (乙) 和33.6% (冷盐水).
结论:
- 与冷盐溶液相比,内支气管内烯没有显著影响程序内全身血压.
- 这些发现支持利弗林在控制呼吸道出血方面的血管和全身安全性.
- 烯呈现了一个可行的替代品,以上腺素用于局部呼吸道血液静止.
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