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Updated: Jun 26, 2025

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治疗耐药抑郁症的全基因组协会研究:具有代谢特征的共享生物学

JooEun Kang1, Victor M Castro1, Michael Ripperger1

  • 1Division of Genetic Medicine, Department of Medicine, and Vanderbilt Genetics Institute (Kang, Morley, Han, Ruderfer), Department of Psychiatry (Castro, Kim, Ge, McCoy, Perlis) and Center for Quantitative Health (Castro, Kim, McCoy, Perlis), Massachusetts General Hospital, Boston; Research Information Science and Computing, Mass General Brigham, Somerville, Mass. (Castro); Department of Psychiatry, Center for Disease Neurogenomics, Friedman Brain Institute, Department of Genetics and Genomic Sciences, Icahn Institute for Data Science and Genomic Technology, and Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York (Venkatesh, Burstein, Voloudakis, Roussos); Mental Illness Research, Education, and Clinical Center (VISN 2 South), James J. Peters VA Medical Center, Bronx, N.Y. (Venkatesh, Burstein, Voloudakis, Roussos); Autism and Developmental Medicine Institute, Geisinger, Lewisburg, Pa. (Linnér, Chabris); Department of Economics, Leiden University, Leiden, the Netherlands (Linnér); Phenomic Analytics and Clinical Data Core (Rocha) and Population Health Sciences (Hu), Geisinger, Danville, Pa.; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei (Feng).

The American journal of psychiatry
|May 15, 2024
PubMed
概括

治疗耐药性抑郁症 (TRD) 的遗传分析揭示了与代谢特征共同的生物学,并确定了两个新的遗传位置. 这项研究提高了我们对TRD的理解.

关键词:
抑郁症 抑郁症 抑郁症 抑郁症电疗法 (ECT) 是一种电疗法.遗传学 / 基因组学严重的抑郁症 严重的抑郁症治疗耐药性抑郁症的治疗方法

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