肠道微生物组组成对社会决策的影响
Marie Falkenstein1, Marie-Christine Simon2, Aakash Mantri2,3
1Control-Interoception-Attention Team, Sorbonne Université, Paris Brain Institute (ICM), Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, 47 boulevard de l'Hôpital, 75013 Paris, France.
PNAS nexus
|May 15, 2024
概括
一种协生 (益生菌和益生菌) 饮食干预通过增加社会惩罚来增强利他主义行为. 这种肠道微生物组调节可能涉及多巴胺前体氨酸水平.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 行为经济学是一种行为经济学.
背景情况:
- 肠道微生物组影响社会情感行为和临床条件.
- 它在健康个体的社会决策中的作用在很大程度上是未知的.
研究的目的:
- 研究协生干预对社会决策的因果关系.
- 探索与利他主义相关的肠道-微生物群-大脑-行为轴.
主要方法:
- 一个7周的饮食干预使用协生菌与安慰剂.
- 利用最后通游戏来评估利他主义的社会惩罚行为.
- 测量了禁食状态的血清氨酸水平.
主要成果:
- 协生干预显著增加了参与者参与社会惩罚的意愿.
- 这种行为变化与改变的氨酸水平相关.
- 表明肠道微生物群,多巴胺前体的可用性和社会行为之间存在联系.
结论:
- 通过协生菌来调节肠道微生物群可以影响社会决策.
- 肠道-微生物群-大脑轴,可能涉及氨酸,在利他主义行为中发挥作用.
- 挑战人类行为的纯粹理性的经济模式.
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