在第三级护理医院的COVID-19患者中嗅觉功能障碍;一个跨部门观察性研究
Sreedevi Nunkappa Thippeswamy1, Kamalesh Thagadur Nataraju2
1Department of ENT, JJM Medical College, Davanagere, Karnataka, India.
Iranian journal of otorhinolaryngology
|May 15, 2024
概括
嗅觉功能障碍,包括厌氧和缺血症,影响了31.87%的COVID-19患者. 这种症状与血清费里廷的增加相关,这表明它可能表明疾病的严重程度.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- COVID-19与嗅觉功能障碍 (OD) 的高发病率有关,影响了诊断和患者管理.
- 在COVID-19中早期识别OD对于及时隔离,诊断和治疗至关重要.
- 了解COVID-19患者中鼻腔症状,特别是OD的流行程度至关重要.
研究的目的:
- 确定中鼻症状的患病率,重点关注嗅觉功能障碍 (OD).
- 分析COVID-19患者的OD和炎症标志物之间的相关性.
- 调查OD作为COVID-19严重程度的潜在指标.
主要方法:
- 对160名COVID-19患者进行了一项横截面观察性研究.
- 嗅觉功能障碍被评估并与炎症标志物和中鼻症状进行比较.
- 患者的随访持续到医院出院或死亡.
主要成果:
- 在160名COVID-19患者中,31.87%的人患有嗅觉功能障碍 (厌氧/缺氧).
- 无/低的平均持续时间为9.92天.
- 嗅觉功能障碍与血清费里水平显著相关 (p=0.0453).
结论:
- 在COVID-19患者中,显著比例的患者出现了厌氧/缺血症.
- 在COVID-19中嗅觉功能障碍与疾病严重程度相关.
- 血清费里水平和嗅觉功能障碍可以作为COVID-19严重程度的替代标记.
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