设计一个个性化药物坚持释放套件的概念里瓦洛克萨班的利瓦洛克萨班
Gretchen M Stern1, Jamie M Pitlick2,3, Zachary A Stacy2,4
1Clinical Pharmacist, Brigham and Women's Hospital, Boston, Massachusetts.
个性化里瓦罗克萨班患者坚持套件 (R-PAKs) 已开发,以改善静脉血栓栓塞 (VTE) 患者的药物坚持和支持剂量过渡. 这些套件旨在减少不良事件,增强患者教育和后续护理.
科学领域:
- 药理学 药理学是指药理学的学科.
- 患者的坚持 患者的坚持
- 药物管理 药物管理
背景情况:
- 缺乏对利瓦洛克萨班的监测会增加由于剂量不正确或粘附不良而导致不良事件的风险.
- 从每天两次服用15毫克转换为每天一次服用20毫克的患者需要加强支持,以成功改变治疗方案.
- 现有的坚持工具无法完全满足接受里瓦洛克萨班治疗的患者的特定需求.
研究的目的:
- 开发个性化的里瓦洛克萨班患者坚持套件 (R-PAKs).
- 为了改善坚持和促进从15毫克两次到20毫克四次剂量的过渡,用于静脉血栓塞栓症 (VTE) 治疗.
- 增强患者教育,强化和对利瓦洛克萨班使用者的后续护理.
主要方法:
- 进行了对Rivaroxaban药物信息和坚持工具的审查.
- 确定了患者关键问题,包括剂量理解,服用时间,不良反应,遵守和随访.
- 创建了R-PAK,包括教育手册,提醒卡和个性化的28天药片组织者,带有彩色编码的贴纸.
- 在试点阶段,向100名患者分发了药剂师教育套件.
主要成果:
- 试点阶段涉及创建和分发100个R-PAKs.
- 每个套装都包含量身定制的教育材料和药丸组织器,以支持坚持.
- 彩色编码的贴纸和个性化的分隔器有助于管理剂量过渡.
- 在一个社区教学医院,R-PAK正在被用于新诊断的VTE患者,这些患者正在接受里瓦洛克萨班治疗.
结论:
- R-PAKs有效地支持Rivaroxaban的坚持和VTE患者的剂量转换.
- 个性化药物盒概念可以适应其他需要高度遵守或剂量调整的药物.
- 通过R-PAK增强的患者支持可以减轻与不正确药物使用相关的风险.
更多相关视频
14:38Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
09:49Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
Published on: December 28, 2021
相关概念视频
Discharge Summary Forms
Here's a detailed look at the key components and guidelines for preparing a discharge summary:
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Dosage Regimen: Fixed Dose
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Rational Dosage Regimen: Maintenance Dose and Loading Dose
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
Drug Distribution: Plasma Protein Binding
