一个患有门静脉血栓症的患者的三重打击
Elamein Yousif1, Elamin Dahawi2, Sarah Premraj3
1Derriford Hospital, University Hospitals Plymouth NHS foundation Trust, Plymouth, UK.
Archive of clinical cases
|May 15, 2024
概括
一种轻微的COVID-19感染,口服避孕药和V因子莱登突变结合在一起,导致一个年轻女子的门静脉血栓形成. 及时的抗凝剂导致显著改善.
科学领域:
- 内部医学 内部医学
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
背景情况:
- SARS-CoV-2 感染与血栓栓塞事件的风险增加有关.
- 患有遗传或获得的前血栓状况的人面临COVID-19后血栓形成的风险较高.
- 门静脉血栓症 (PVT) 是一种不常见的血栓事件,特别是在没有典型风险因素的年轻人中.
研究的目的:
- 在轻微的COVID-19感染后,报告一个年轻女性的门静脉血栓症 (PVT) 病例.
- 调查该患者PVT的促成因素,考虑到她使用口服避孕药和潜在的血栓友.
- 强调在异常血栓形成的情况下考虑COVID-19感染和血栓性查的重要性.
主要方法:
- 一份病例报告显示,一名30岁的女性患者在从COVID-19中康复后出现了急性腹痛.
- 实验室调查,包括炎症标志物和血栓友爱检查.
- 用对比增强的腹部计算机断层扫描 (CT) 扫描来诊断门静脉血栓症 (PVT).
主要成果:
- 患者在轻度COVID-19感染后三天出现了急性腹痛.
- 腹部CT扫描证实了门静脉血栓形成 (PVT).
- 血栓过敏查揭示了异合体V因子莱登突变 (FVL),确定了COVID-19,口服避孕药使用和FVL的组合作为致病因素.
结论:
- 感染COVID-19,使用口服避孕药和V因子莱登突变代表了门静脉血栓形成的重要危险因素.
- 在异常部位的血栓形成患者中,检查最近的COVID-19感染和血栓友爱症至关重要.
- 建议停止潜在的有助于治疗的药物,并与抗凝血疗法一起用于管理这种病例.
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