对于COVID-19感染后疲劳的传统,补充和整合医学:随机对照试验的系统审查
Xiao-Ying Chen1, Chun-Li Lu2, Qian-Yun Wang1,3
1Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Integrative medicine research
|May 15, 2024
概括
传统,补充和整合医学 (TCIM) 显示了减少长期COVID患者慢性疲劳的潜力. 需要进一步的高质量研究来证实这些关于TCIM疗效的初步发现.
科学领域:
- 综合医学是一个整体的医学.
- 在COVID-19研究研究中.
- 公共卫生 公共卫生
背景情况:
- 慢性疲劳是COVID-19感染后的一个显著和持续的症状,通常被称为长期COVID.
- 评估传统,补充和整合医学 (TCIM) 干预措施的有效性对于管理COVID-19后疲劳至关重要.
研究的目的:
- 评估TCIM的有效性和安全性,以缓解COVID-19后患者的疲劳.
- 综合从长期COVID疲劳TCIM干预的随机对照试验 (RCT) 的证据.
主要方法:
- 进行了RCT的系统审查,搜索了10个数据库,查找到2023年4月12日的英语和中文文献.
- 偏差风险 (RoB) 和推评估,开发和评估 (GRADE) 工具的分级用于评估研究质量和证据确定性.
- 影响估计报告为风险比率 (RR) 或平均差异 (MD) 与95%置信区间 (CI).
主要成果:
- 分析了13项涉及1632名参与者的RCT.
- 具体的TCIM干预措施,包括Bufei Huoxue草药囊和Ludangshen草药液,证明了减少疲劳症状的潜力.
- 与传统中医疗康复相结合的青金益智颗粒也显示,与单独康复相比,疲劳症状有所减少.
- 由于对偏见和不准确性风险的担忧,证据的确定性被评为低至非常低. 没有报告任何严重的不良事件.
结论:
- 初步证据表明,某些TCIM干预措施可能有助于减少与长期COVID相关的疲劳.
- 需要进行更大规模,高质量的随机对照试验,并进行更长的随访期,以验证这些发现并制定最终的治疗指南.
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