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Updated: Jun 26, 2025

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Published on: January 12, 2024

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在有针对性的蛋白质降解中,PROTAC诱导的蛋白质结构动态

Kingsley Y Wu, Ta I Hung, Chia-En A Chang

    bioRxiv : the preprint server for biology
    |May 15, 2024
    PubMed
    概括

    针对蛋白质溶解的金马 (PROTACs) 使用链接器来控制蛋白质降解. 这项研究揭示了PROTAC链接器动态如何影响标蛋白的泛化和降解效率.

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