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Updated: Jun 26, 2025

High-throughput Identification of Synergistic Drug Combinations by the Overlap2 Method
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Published on: May 21, 2018

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SAFER:以注意力为基础的子超图神经网络,用于预测对剂量组合的有效反应

Yi-Ching Tang1, Rongbin Li1, Jing Tang2

  • 1Center for Safe Artificial Intelligence for Healthcare, McWilliams School of Biomedical Informatics, the University of Texas Health Science Center at Houston, Houston, United States.

Research square
|May 15, 2024
PubMed
概括

人工智能模型可以预测癌症中的药物协同作用,但与剂量和动态网络作斗争. 一个新的图形模型SAFER准确地预测了剂量依赖的药物协同作用,并确定了关键的生物途径.

关键词:
超图表示学习学习学习超图表示.背景感知模型的背景感知模型剂量反应药物组合数据药物组合的预测和预测.图表显示注意力机制.

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