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Updated: Jun 26, 2025

Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets
10:52

Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets

Published on: August 13, 2016

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由BuGZ介导的Aurora-A凝结有助于其线粒中心体功能

Hui Zheng1,2, Qiaoqiao Zhang1,2, Xing Liu3

  • 1Laboratory for Aging and Cancer Research, Frontiers Science Center Disease-related Molecular Network, State Key Laboratory of Respiratory Health and Multimorbidity and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.

iScience
|May 15, 2024
PubMed
概括

在线粒分裂过程中, Aurora-A 激酶在中心体中经历液体-液体相分离 (LLPS). 这种LLPS受其无序区域和分子内相互作用的影响,会影响中枢细胞成熟和形形成,而BuGZ则增强这些功能.

关键词:
生物物理学的生物物理.细胞生物学 细胞生物学细胞生物学的功能方面.

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