高度主义,生长激素治疗和社会功能:一个整体的方法来解决持续的临床挑战
Camilia Kamoun1, Emily A Largent2,3, Adda Grimberg3,4,5
1Department of Pediatrics, Division of Endocrinology, University of North Carolina, Chapel Hill, North Carolina.
Current opinion in pediatrics
|May 15, 2024
概括
再组合人类生长激素 (rhGH) 治疗矮身可能不会直接改善心理社会福祉. 心理社会因素,而不仅仅是身高,是改善儿童生活质量和自尊的关键.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 心理社会健康 心理健康
- 儿童发展 儿童发展
背景情况:
- 重组人体生长激素 (rhGH) 越来越多地用于治疗没有生长激素缺乏症的儿童的矮身.
- 将增高与改善心理社会福祉联系在一起的证据是不一致的,缺乏高质量的数据.
研究的目的:
- 审查最近关于增高和儿童心理社会福祉之间的关系的证据.
- 评估rhGH治疗对改善心理社会结果的有效性.
主要方法:
- 对最近关于矮身和心理社会幸福感的研究进行系统审查.
- 分析身高增长与生活质量,自尊和社会功能之间的关联.
主要成果:
- 增高和心理社会福祉之间的联系是复杂的,不仅仅取决于增高.
- 心理社会因素,如关于身高的信念,社会支持和应对机制显著影响幸福感.
- 身高可能比目前的临床模型表明的对幸福感的贡献要小.
结论:
- 矮身的临床管理应采用整体方法.
- 建议将心理社会干预与rhGH治疗一起或作为其替代方案进行整合.
- 专注于心理社会因素可以提高矮身患者的生活质量和自尊.
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