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Updated: Jun 26, 2025

The Assembly and Application of 'Shear Rings': A Novel Endothelial Model for Orbital, Unidirectional and Periodic Fluid Flow and Shear Stress
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Published on: October 31, 2016

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剪切应激和病理生理学PI3K参与血管形

Salim Abdelilah-Seyfried1, Roxana Ola2

  • 1Institute of Biochemistry and Biology, Potsdam University, Potsdam, Germany.

The Journal of clinical investigation
|May 15, 2024
PubMed
概括

在PIK3CA中获得功能的突变会导致称为PIKopathies的血管异常. 这些受流体剪切应力的影响,这表明PI3K信号是理解和治疗这些疾病的关键.

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