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Updated: Jun 26, 2025

Isolation of Macrophage Subsets and Stromal Cells from Human and Mouse Myocardial Specimens
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向心律失常性巨细胞:从心律失常性心肌病学上吸取教训

Thassio Mesquita, Eugenio Cingolani

    The Journal of clinical investigation
    |May 15, 2024
    PubMed
    概括

    免疫介导的损伤有助于心律失常性心肌病 (ACM). 抑制核因子 κ-B (NF-κB) 和向单细胞衍生的巨细胞减少了小鼠的ACM特征,这表明了ACM患者的新免疫疗法.

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    Isolation and Culture of Resident Cardiac Macrophages from the Murine Sinoatrial and Atrioventricular Node

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    Mechanism of Cardiac Arrhythmias

    Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
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