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Updated: Jun 26, 2025

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
11:27

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

Published on: May 13, 2020

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使用一种共同的催化机制,对 (βα) 8-桶折叠甲-四二氨基缩酶的突变和结构研究

Manuel Gehl1, Ulrike Demmer2, Ulrich Ermler2

  • 1Max Planck Institute for Terrestrial Microbiology, Marburg, Germany.

Protein science : a publication of the Protein Society
|May 15, 2024
PubMed
概括

这项研究揭示了一种常见的甲-四二氨酸减少酶的催化机制,尽管其序列相同性较低,但这表明了趋同的进化. 结构和突变分析阐明了这些C1代谢酶的关键中间体和进化途径.

关键词:
催化机制是一种催化机制.晶体结构 晶体结构进化 演化 演化 演化 演化 演化 演化 演化甲四基叶酸减少酶.甲 - 四水甲 - 二烯降解酶.

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