在非传染性脑膜炎中使用皮质类固醇 - - 台湾专家共识
Yo-Chen Chang1,2,3, Tzu-En Kao4, Ching-Long Chen5
1Department of Ophthalmology, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Annals of medicine
|May 15, 2024
概括
皮质类固醇 (CS) 对非传染性脑膜炎至关重要,但它们的使用需要仔细规划. 这份共识为台湾从业人员提供了关于CS的管理,逐渐减少和替代治疗方法的指导方针,以改善患者护理.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 非传染性脑膜炎的管理在临床实践中存在挑战.
- 皮质类固醇 (CS) 是一种主要的治疗方式,但需要战略性应用.
- 台湾的临床实践和卫生政策需要具体的治疗指南.
研究的目的:
- 建立关于在台湾治疗非传染性脑膜炎时最佳使用皮质类固醇 (CS) 的共识.
- 审查用于CS在脑膜炎的施用方法,优点,缺点和替代疗法.
- 将治疗策略与当前的证据和当地卫生政策保持一致.
主要方法:
- 一个由十名眼科医生和一名风湿病学家组成的小组召开会议,审查相关文献.
- 从1996年到2023年,在主要数据库 (Cochrane,EMBASE,Medline,PUBMED,Web of Science) 进行了文献搜索.
- 共识声明通过公开投票确定,要求达成>70%的协议,然后进行专家审查和讨论.
主要成果:
- 开发了一个流程图和九个共识声明.
- 这些指导方针涵盖了CS的重要性,局部CS使用,周期性,静脉内膜和全身CS治疗的指示.
- 建议包括逐渐减少和停止局部和系统CS的方法.
结论:
- 皮质类固醇仍然是治疗非传染性脑膜炎的基石.
- 战略性管理,逐渐减少和考虑替代疗法对于有效的患者护理至关重要.
- 该共识为台湾的医生提供了实际的指导方针,整合了基于证据的医学和当地环境.
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