2020年巴西状细胞病和COVID-19相关的死亡率,2020年
1Universidade de São Paulo (retired), Faculty of Public Health, Department of Epidemiology - São Paulo (SP), Brazil.
概括
2020年期间,COVID-19在巴西显著影响了状细胞疾病的死亡率,改变了死亡原因,年龄分布和区域模式. 这项研究强调了大流行.
科学领域:
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 严重急性呼吸道综合征-CoV-2 (COVID-19) 是一种新型病原体,其中死亡率是疾病严重程度的关键指标.
- 状细胞疾病 (SCD) 是一种遗传性血液疾病,可以增加对感染和并发症的脆弱性.
研究的目的:
- 在巴西COVID-19大流行期间描述与状细胞疾病相关的死亡模式.
- 从原因,年龄和地理分布来分析COVID-19对SCD相关死亡的影响.
主要方法:
- 利用来自巴西死亡信息系统的2020年临时死亡数据.
- 在数据调查中采用多重死亡原因方法.
主要成果:
- 2020年,发生了688起与SCD相关的死亡,而COVID-19在78起案件中是相关原因.
- SCD死亡主要影响年轻人 (25-49岁),而COVID-19死亡发生在老年人中.
- 主要的潜在死亡原因是SCD,传染病/寄生病 (包括COVID-19),以及循环系统疾病. 败血症和呼吸衰竭是主要的相关原因.
结论:
- COVID-19死亡改变了与SCD相关的死亡率趋势,包括2020年巴西的死亡原因,死亡年龄和区域分布.
- 这些发现强调了大流行对状细胞病患者的重大影响.
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