在MIS-C患者的随访中,是否应该使用大动脉硬度参数?
Hatice Uygun1, Celal Varan2, Capan Konca3
1Department of Pediatric Infectious Disease, Gaziantep University School of Medicine, University Boulevard, Sehitkamil-Gaziantep, 27310, Turkey. ozhanhatice@hotmail.com.
The international journal of cardiovascular imaging
|May 15, 2024
概括
儿童多系统炎症综合征 (MIS-C) 可能导致心血管问题,但大多数心声回声检查结果在六个月内得到改善. 对于MIS-C患者,建议至少持续六个月的心血管监测.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 传染性疾病 传染性疾病
- 心血管研究研究心血管研究
背景情况:
- 儿童多系统炎症综合征 (MIS-C) 是一种严重的疾病,影响多个器官,包括心脏.
- 了解MIS-C对心血管的影响对于患者管理和长期结果至关重要.
研究的目的:
- 评估MIS-C对儿童的短期和长期心血管影响.
- 为了比较MIS-C患者与对照者的心声和大动脉硬度参数.
- 为了确定心血管异常的恢复轨迹在诊断后六个月内.
主要方法:
- 这是一项回顾性研究,将38名MIS-C患者与55名对照人进行比较.
- 评估了标准心声回声测量和大动脉硬度参数.
- 诊断时进行了比较,并在六个月后进行了随访.
主要成果:
- 在诊断时,MIS-C患者表现出较高的 mitra 膜缺陷率 (42%),左心室缩功能障碍 (36%) 和冠状动脉扩张 (31%).
- 与对照组相比,MIS-C患者的射出分数和脉冲压明显较低 (p<0.01,p=0.045).
- 大动脉硬度参数在MIS-C患者中升高,大动脉延伸度有显著差异 (p=0.029),但这些在六个月后正常化.
结论:
- 在MIS-C诊断中检测到的许多心血管异常在六个月内消失.
- 大动脉硬度参数,虽然最初较高,但显示趋向于正常化.
- 在被诊断为MIS-C的儿童中,至少需要进行六个月的心血管随访.
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