纤维肌痛中的集群分析:系统性审查
Anna Carolyna Gianlorenço1,2, Valton Costa1,2, Walter Fabris-Moraes2
1Neuroscience and Neurological Rehabilitation Laboratory, Physical Therapy Department, Federal University of Sao Carlos, Sao Carlos, SP, Brazil.
Rheumatology international
|May 15, 2024
概括
纤维肌痛综合征 (FMS) 患者子组存在,通过集群分析确定. 这些多样化的个人资料突出了为FMS管理提供量身定制的治疗和更好的医疗保健资源配置的需要.
科学领域:
- 类风湿病学 类风湿病学
- 医疗信息学 医疗信息学
- 精神病学是一个精神病学.
背景情况:
- 纤维肌痛综合征 (FMS) 呈现出复杂多样的症状.
- 集群分析已被用于探索这些症状模式,并确定患者子组.
研究的目的:
- 系统地审查和综合现有关于纤维肌痛综合征集群分析的研究.
- 确定FMS集群研究中使用的常见变量,方法,患者子组和评估指标.
主要方法:
- 根据PRISMA指南进行了系统审查.
- 在主要数据库 (PubMed,Embase,Web of Science,Cochrane Central) 进行了搜索,搜索到2024年1月发表的研究.
- 包括的研究使用集群分析来检查FMS患者的身体,心理,临床或生物医学变量.
主要成果:
- 包括39项研究,主要使用横截面设计.
- 确定的患者个人资料各不相同,包括2-4个严重程度/调整水平,2-3个基于症状的群体 (疼痛与疲劳,疼痛敏感性) 和个性/心理脆弱性个人资料.
- 跨集群也观察到对药理和多模式治疗的不同反应.
结论:
- 在FMS中存在不同的患者个人资料,这凸显了个性化治疗策略的必要性.
- 通过认可这些子组,可以提高医疗保健资源的有效分配.
- 建议进行进一步的研究,以验证集群发现,并探索更客观的测量工具.
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