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Updated: May 10, 2026

Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay System
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使用基于结构的虚拟查方法来发现潜在的LSD1抑制剂

Zhehao Fan1,2, Xiaofeng Liu3, Ning Wang1,2

  • 1Institute of Translational Medicine, Medical College, Yangzhou University, Jiangyangzhonglu No. 136, Yangzhou, Jiangsu, China.

Journal of cancer research and clinical oncology
|May 15, 2024
PubMed
概括

研究人员确定ZINC10039815是氨酸特异性脱甲酶1 (LSD1) 的强有力的抑制剂,这是癌症治疗的关键标. 这种化合物通过阻断LSD1活性来开发新的抗癌药物具有前途.

关键词:
停靠对接 停靠对接抑制剂的抑制剂一个LSD1一个LSD1分子动力学模拟模型

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