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年轻人与患有细胞癌的老年人进行机器人辅助部分切除术:倾向性得分匹配分析
Ryotaro Tomida1, Tomoya Fukawa2, Yoshito Kusuhara1
1Department of Urology, Tokushima University Graduate School of Biomedical Sciences, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
World journal of urology
|May 15, 2024
概括
机器人辅助部分切除术 (RAPN) 的结果在年轻患者和老年患者之间是可比的. 然而,接受RAPN的老年人经历了更严重的并发症,需要仔细的手术前评估和术后护理.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
- 老年人手术是一门老年人手术.
背景情况:
- 机器人辅助部分切除术 (RAPN) 是对细胞癌 (RCC) 的最小侵入性技术.
- 评估RAPN在老年人群中的安全性和有效性对于手术决策至关重要.
研究的目的:
- 为了比较较年轻 (<75岁) 和老年 (≥75岁) T1 RCC患者之间的RAPN手术结果.
- 具体评估RAPN在老年患者中的安全性和结果.
主要方法:
- 在2013年至2022年期间,在日本五个机构对559名T1 RCC患者接受RAPN治疗的回顾性分析.
- 倾向性得分匹配 (PSM) 用于平衡年轻和年长患者组之间的基线特征.
- 在匹配的年轻和年长的队列之间比较了手术结果和并发症率.
主要成果:
- 在PSM之后,204名年轻患者和102名老年患者被纳入分析.
- 患者的特征,不包括年龄,在匹配组之间是相似的.
- 较年长的组与较年轻的组相比 (3.0%,P=0.045) 的重大并发症率显著更高 (8.8%).
结论:
- 对于T1 RCC的RAPN手术结果在年轻患者和老年患者之间是可比的.
- 接受RAPN的老年患者面临更高的重大并发症风险.
- 对于接受RAPN的老年患者,建议加强手术前评估和量身定制的术后管理.
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