四维计算机断层扫描作为一线成像在原发性甲状腺功能障碍症,一个回顾性比较传统成像在一个主要是单个腺瘤的人口
Jorian P Krol1,2, Frank B M Joosten3, Hans de Boer4
1Department of Radiology & Nuclear Medicine, Rijnstate Hospital, Wagnerlaan 55, Arnhem, 6815AD, The Netherlands. j.p.krol@utwente.nl.
EJNMMI reports
|May 15, 2024
概括
四维CT是一种比超声波和SPECT更敏感的第一线成像工具,比超声波和SPECT更为敏感,减少了对额外程序的需求. [18F]胆PET/CT对于难以局部化仍然至关重要.
科学领域:
- 放射学 放射学是一门学科.
- 核医学就是核医学.
- 内分泌学 在内分泌学.
背景情况:
- 初级甲状腺功能障碍症诊断通常依赖于手术前成像来定位甲状腺腺瘤.
- 传统的成像技术结合了超声波和99mTc-sestamibi SPECT技术,但其有效性各不相同.
- 四维CT (4D-CT) 为副甲状腺局部化提供了先进的成像功能.
研究的目的:
- 为了比较4D-CT的诊断性能作为一线成像模式与超声波和[99mTc]Tc-Sestamibi SPECT用于原发性副甲状腺症的传统组合.
- 为了评估灵敏度,积极的预测值,以及在两种方法中需要额外的成像.
主要方法:
- 在105名患有初级甲状腺功能障碍症的患者中进行了手术前成像的回顾性审查,这些患者在2012年至2021年期间接受了甲状腺切除术.
- 患者被分为两组:一组接受超声波/[99mTc]Tc-Sestamibi SPECT作为一线成像 (n=54),另一组接受4D-CT (n=51).
- 灵敏度和积极预测值在患者,横向化和局部化水平上计算; 额外的成像要求也被评估.
主要成果:
- 与超声波/[99mTc]Tc-Sestamibi SPECT相比,4D-CT显示患者和局部检测的灵敏度明显更高 (分别为70.6%与51.9%和60.8%与35.2%).
- 虽然4D-CT对横向化的敏感性更高,但它没有达到统计学意义 (62.7%与44.4%对比).
- 两种方法的积极预测值是可比的,但4D-CT需要较少的额外成像程序 (27.4%) 与传统方法 (44.4%) 相比.
结论:
- 与联合超声波和[99mTc]Tc-Sestamibi SPECT方法相比,四维CT作为一种更敏感的单一一线成像模式用于原发性副甲状腺功能障碍.
- 使用4D-CT作为最初的成像策略可以减少对后续诊断程序的需求.
- [18F]胆PET/CT,尽管成本高昂,但在所有其他成像方法都产生负面结果时,它被证明是局部化副甲状腺腺瘤的最有效方法.
相关概念视频
01:10Computed Tomography
4.5K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.5K
01:29Positron Emission Tomography
4.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.2K