关于儿童重症监护病房参与研究的种族和民族差异
Sarah L Mayer1, Michelle R Brajcich1, Lionola Juste1
1Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia.
JAMA network open
|May 15, 2024
概括
黑人和西班牙裔家庭以及那些面临语言或社会经济障碍的家庭在儿科重症监护室 (PICU) 的研究参与率较低. 较低的申请率部分解释了对黑人儿童的同意减少,突出了减少差异的机会.
科学领域:
- 儿科重症监护的研究研究.
- 临床试验招生报名
- 卫生公平性健康公平性
背景情况:
- 研究同意率的差异在成人和儿科设置中得到了记录.
- 关于儿科重症监护室 (PICU) 招生挑战的数据有限.
- 由于高压力和时间敏感性,PICU环境对学习入学造成了独特的困难.
研究的目的:
- 在PICU环境中调查社会人口统计因素与研究方法/同意率之间的关联.
- 确定种族,族裔,语言,宗教和社会贫困指数 (SDI) 是否影响PICU研究入学.
- 评估较低的申请率在多大程度上调解了同意差异.
主要方法:
- 从2011年到2021年,在单个PICU进行了回顾性队列研究.
- 包括有资格参加需要潜在同意的研究的患者.
- 多变量回归分析了社会人口统计因素 (种族,种族,语言,宗教,SDI) 和接近/同意率之间的关联.
主要成果:
- 黑人和西班牙裔家庭,非英语家庭,穆斯林家庭以及具有较高SDI的家庭的接触率和同意率较低.
- 与白人儿童相比,黑人儿童的同意率较低 (调整后OR,0.68).
- 较低的接触率占黑人儿童同意率降低的51% .
结论:
- 社会人口统计学因素与PICU研究的同意率较低有关,部分原因是不同的方法率.
- 调查结果表明,减少儿童重症监护研究参与差异的潜在策略.
- 解决方法差异对于提高PICU研究入学率的公平性至关重要.
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