身体活动和冠状动脉化在男性和女性的进展
Kerem Shuval1, David Leonard1, Laura F DeFina1
1The Cooper Institute, Dallas, Texas.
JAMA cardiology
|May 15, 2024
概括
在健康的成年人中,高体力活动 (PA) 并没有随着时间的推移加速冠状动脉 (CAC) 的进展. 这项研究没有发现PA体积和CAC进展之间存在关联,这表明运动不会使动脉化恶化.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 运动生理学 运动生理学
背景情况:
- 截面研究表明,高体力活动 (PA) 可能与冠状动脉 (CAC) 患病率增加相关.
- 大量的PA对CAC纵向进展的影响仍然不太清楚.
研究的目的:
- 调查在基线和随访期间测量的体力活动 (PA) 水平与冠状动脉 (CAC) 随时间的进展之间的关联.
- 为了确定大量的PA是否会影响看似健康的个体中CAC积累的速度.
主要方法:
- 一项对8771名40岁以上的健康男性和女性进行的队列研究,这些男性和女性进行了连续的预防性医疗访问.
- 在平均7.8年的随访期间收集了PA和CAC测量值.
- 负双项和比例危险回归模型分析了CAC进展率和风险值.
主要成果:
- 平均每年CAC进展率在男性中为28.5%,在女性中为32.1%,独立于PA体积.
- 在PA体积 (每500MET-min/week) 和CAC进展率之间没有发现显著的关联.
- 基线PA水平没有预测进展到临床显著的CAC得分 (≥100AU).
结论:
- 身体活动量与健康个体的冠状动脉的进展无关.
- 结果表明,高水平的PA在这个队列中不会加速动脉化.
- 这项研究有助于理解运动与亚临床动脉样硬化进展之间的关系.
更多相关视频
04:40Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
15.2K
08:02Author Spotlight: Enhanced Quantification of Cardiovascular Calcification Progression for Longitudinal Micro PET/CT Studies in Small Research Animals
Published on: November 15, 2024
591
相关概念视频
Exercise and Cardiac Output
998
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
998
Exercise and Cardiovascular Response
791
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
791
Imaging Studies for Cardiovascular System III: X-Ray
178
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
178
