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Updated: Jun 26, 2025

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通过激活JAK2 / STAT3通路,CDKN2A抑制了铁亡,以调节宫状细胞癌中的西斯普拉丁抗性

Xiang Yong1,2,3, Yanling Zhang4, Heng Tang2,3

  • 1Department of Pathology, The Second Affiliated Hospital of Anhui Medical University, Hefei City.

Anti-cancer drugs
|May 15, 2024
PubMed
概括

循环素依赖性激酶抑制剂2A (CDKN2A) 通过JAK2/STAT3通路抑制铁亡,促进子宫癌中对西斯普拉丁的耐药性. 减少CDKN2A可以增强铁亡并克服治疗耐药性.

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