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Updated: Jun 26, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

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发现了针对PD-L1/CD73的小型和双功能分子,用于癌症双重免疫疗法

Shuanghu Wang1,2, Zhihua Kong3, Yaru Shi1

  • 1Central Laboratory, Wenzhou Medical University Lishui Hospital, Lishui People's Hospital, Lishui, Zhejiang 323000, China.

Journal of medicinal chemistry
|May 15, 2024
PubMed
概括

CC-5是第一个针对PD-L1和CD73.3的小分子抑制剂. 这种双功能剂有效地抑制了瘤生长,并激活了瘤免疫微环境,显示了癌症免疫治疗的前景.

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