在早期炎症性关节炎队列中,诊断后12个月的心理痛苦
Lucy Zhao1,2,3,4, James Galloway2, Jo Ledingham5
1Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
一半被诊断患有炎症性关节炎 (IA) 的患者经历了心理困扰,影响了他们的生活质量和疾病结果. 早期查和综合心理健康支持对于有效管理IA至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 炎症性关节炎 (IA) 与严重的心理健康挑战有关.
- 在IA中疾病的进展往往会加剧心理痛苦.
- 了解诊断后心理痛苦的趋势对于患者护理至关重要.
研究的目的:
- 评估AI诊断后12个月内心理痛苦的趋势.
- 将心理痛苦与临床结果进行映射.
- 在IA患者中确定痛苦和疾病进展之间的关联.
主要方法:
- 使用国家早期炎症性关节炎审计 (NEIAA) 的前性研究.
- 收集患者报告的结果 (PROs),包括在基线,3个月和12个月的心理困扰 (PHQ4ADS).
- 雇佣混合效应线性回归来分析与痛苦的关联.
主要成果:
- 50.2%的患者在基线报告了心理困扰.
- 三个月后的痛苦降至30.0%,十二个月后降至24.1%.
- 较高的基线痛苦与较差的生活质量,残疾,工作表现和治疗反应有关.
结论:
- 在诊断时,一半的IA患者存在显著的精神健康并发症.
- 心理压力与更糟糕的疾病结果和生活质量有关.
- 对焦虑/抑郁症的普遍查和综合情绪疗法对于IA管理至关重要.
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