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联合宿主-病原体基因组分析识别了与人类NTCP和HLAI类变异相关的B型肝炎病毒突变

Zhi Ming Xu1, Gnimah Eva Gnouamozi2, Sina Rüeger1

  • 1School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland.

American journal of human genetics
|May 15, 2024
PubMed
概括

乙型肝炎病毒 (HBV) 演变表明适应宿主压力. 在NTCP受体和HLA-A中的特定遗传变异会影响HBV突变,影响病毒进入和免疫逃避.

关键词:
输入HBV的入口是HBV.逃生变体的逃生变体进化基因组学是进化的基因组学.乙型肝炎病毒的感染.主体-病原体基因组学免疫遗传学 免疫遗传学选择的选择选择的选择.病毒限制 病毒限制

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