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在睡眠期间量化验证上侧压力信号,以评估睡眠期间的呼吸力度
Luca Cerina1, Gabriele B Papini1,2, Pedro Fonseca1,2
1Electrical Engineering, Technische Universiteit Eindhoven, Eindhoven, Noord Brabant, The Netherlands.
Physiological measurement
|May 15, 2024
概括
腹上压力 (SSP) 传感器为食道压力 (Pes) 和呼吸诱导囊 (RIP) 提供了一种可靠的,非侵入性的替代方案,用于测量睡眠期间的呼吸力度,包括呼吸事件.
科学领域:
- 呼吸系统生理学 呼吸系统生理学
- 睡眠医学 睡眠医学
- 生物医学工程 生物医学工程
背景情况:
- 消化管内压力 (Pes) 是衡量睡眠期间呼吸力度的黄金标准,但在临床上是不切实际的.
- 呼吸诱导囊图 (RIP) 是多睡眠图 (PSG) 中可用的替代方案,但提供了潮体积和流量的间接测量,而不是真正的努力.
- 非侵入性上方突压力 (SSP) 测量显示,它有可能成为更好的呼吸力度指标,此前仅用于阻塞性睡眠呼吸暂停 (OSA) 事件.
研究的目的:
- 对RIP皮带和食道压力 (Pes) 进行广泛验证,以广泛验证外侧压力 (SSP) 信号与RIP带和食道压力 (Pes).
- 评估SSP在检测正常呼吸和各种呼吸事件方面的表现.
- 与既有方法相比,评估SSP在估计呼吸速率和模式相似性的准确性.
主要方法:
- 在临床多眠学 (PSG) 期间同时获取SSP (n=207),Pes (n=20) 和RIP带信号.
- 定制算法用于所有获取信号的呼吸检测.
- 评估SSP信号质量,呼吸速率估计的准确性,以及与RIP和Pes相比的模式相似性,包括呼吸事件期间的分析.
主要成果:
- SSP显示出可靠的呼吸检测,超过75%的灵敏度和积极的预测值,低呼吸速率估计误差.
- SSP与Pes显示出一致性,达到0.72的相关性和80.8%的呼吸模式相似性.
- SSP准确地反映了阻塞性睡眠呼吸暂停 (OSA) 事件的特征,即增加的压力幅度.
结论:
- 背外压力 (SSP) 传感器提供了一种可靠的,非侵入性的方法来测量睡眠期间的呼吸力.
- 在临床睡眠研究中,SSP可以作为食道压力 (Pes) 和呼吸诱导囊 (RIP) 的可行替代品.
- 这项研究为SSP传感器提供了定量验证,支持它们在呼吸力度测量中的更广泛应用.
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