脊柱结构损伤对轴性脊柱关节炎患者的功能负担:适应媒介解?
Marcela Paula Santos Penteado1, Gustavo Gomes Resende2, Ricardo da Cruz Lage2
1M.P.S. Penteado, MD, MS, Graduate Program in Sciences Applied to Adult Health, Faculdade de Medicina da Universidade Federal de Minas Gerais, and Department of Rheumatology, Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte; marcela.penteado@ebserh.gov.br.
轴性脊柱关节炎 (axSpA) 中的脊柱损伤与身体功能有关,但疾病活动和移动性是更强的预测因素. 将部面关节评估添加到放射学得分中并没有改善功能预测.
科学领域:
- 类风湿病学 类风湿病学
- 放射学 放射学是一门学科.
- 临床评估 临床评估
背景情况:
- 轴性脊柱关节炎 (axSpA) 是一种慢性炎症性疾病,主要影响脊柱.
- 脊柱损伤,通过放射评估,是 axSpA 进展的标志.
- 了解脊柱结构变化与功能能力之间的关系对于患者管理至关重要.
研究的目的:
- 研究 axSpA.患者脊柱损伤与功能能力之间的关联.
- 为了比较两种放射性评分系统的性能:修改的冲刺结性脊柱炎脊柱评分 (mSASSS) 和联合结性脊柱炎脊柱评分 (CASSS).
主要方法:
- 用mSASSS和CASSS (包括宫面关节) 分析了101名axSpA患者的X光照.
- 功能能力是使用浴化脊柱炎功能指数 (BASFI) 测量.
- 通过使用经过验证的指数 (BASDAI,ASDAS,BASMI,ASQOL) 来评估疾病活动,流动性和生活质量.
主要成果:
- 巴斯菲显示与生活质量 (ASQOL) 和疾病活性 (BASDAI) 有很强的相关性.
- 疾病活动 (BASDAI) 和流动性 (BASMI) 是身体功能 (BASFI) 的显著独立预测因素.
- 放射性得分 (mSASSS,CASSS) 预测的功能只有当移动性措施被排除在模型之外.
结论:
- 脊柱损伤与axSpA中的身体功能独立相关,但与疾病活动和运动性相比较少.
- 结合性缩性脊柱炎脊柱评分 (CASSS),包括部面关节评估,与单独使用mSASSS相比,没有提高功能能力的预测.
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