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患有心房的患者的左心室小心室与心血管风险增加有关

Mingxiao Li¹, Lan Ren¹, Liu He¹

¹Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, Beijing, China.

Journal of the American College of Cardiology

|May 15, 2024

概括

小左心室 (LV) 尺寸与心房动 (AF) 患者心血管事件风险较高有关. 这一发现对于风险分层和管理小LV的AF患者至关重要.

科学领域:

心脏病学心脏病学
心声回声扫描 (Echocardiography) 是一种心声回声扫描.
临床研究临床研究

背景情况:

在心房动 (AF) 患者中,小左心室 (LV) 的预后意义仍然不确定.
调查LV大小作为AF潜在的不良结构预测因子对于改善患者结果至关重要.

研究的目的:

为了确定小LV大小与大型AF队列中主要心血管事件风险之间的关联.
分析左心室终端透缩维度 (LVEDD) 和心血管结果之间的关系.

主要方法:

利用来自中国-AF注册表的数据,注册了7764名AF患者.
根据LVEDD测量,将LV尺寸分为正常,小和大组.
采用考克斯回归模型来评估复合心血管事件 (心血管死亡,中风,栓塞,大出血) 的风险.

主要成果:

在4.0%的患者中观察到小LV,并且独立地与复合心血管事件 (aHR: 1.54) 和心血管死亡 (aHR: 1.94) 的风险增加有关.
小 LV 也与较高的重大出血风险相关 (aHR: 2.21).
在LVEDD和复合心血管事件 (P<0.001) 之间发现了显著的U形关系.

结论:

小LV是AF患者心血管事件风险增加的独立预测因子.
这些发现强调了在AF患者的风险分层和管理策略中考虑LV大小的重要性.
这项研究强调了AF中LV维度的预后价值.

关键词:

心房动是心房动的一种.心血管疾病的风险.导管切除导管切除导管切除导管切除在左心室的左心室.一个潜在的队列.

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