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Updated: Jun 26, 2025

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IRE1α通过调节谷氨合成来确定铁灭的敏感性

Dadi Jiang1, Youming Guo2, Tianyu Wang2,3

  • 1Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. djiang2@mdanderson.org.

Nature communications
|May 15, 2024
PubMed
概括

需要伊诺西的酶1 (IRE1α) 通过控制谷氨合成来调节铁灭的敏感性. 抑制IRE1α可减少铁亡和损伤,提供一种潜在的治疗策略.

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