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Updated: Jun 26, 2025

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用于治疗肥胖症的GLP-1导向NMDA受体对抗作用

Jonas Petersen1,2, Mette Q Ludwig1, Vaida Juozaityte1

  • 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Nature
|May 15, 2024
PubMed
概括

一种新型双模分子结合了N-甲基-D-阿斯巴达酸 (NMDA) 受体对抗性和葡萄糖类-1 (GLP-1) 受体对抗性. 这种方法有效地扭转了动物模型中的肥胖和代谢疾病症状.

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