患有慢性病的年轻患者的病:随机对照试验的发现
Karolin Charlotte Hoefer1, Anna Greta Barbe1, Anne Adams2
1Department of Operative Dentistry and Periodontology, Faculty of Medicine, University Hospital of Cologne, University of Cologne, Cologne, Germany.
Head & face medicine
|May 15, 2024
概括
患有慢性病 (CKD) 的年轻患者经常经历口臭,主要是由二甲基硫化物引起的. 虽然密集的口腔护理减少了舌头的涂层,但在本研究中,它并没有显著降低挥发性硫化合物.
科学领域:
- 口腔健康研究 口腔健康研究
- 腎臟病學 (nephrology) 是一種醫學專業.
- 儿科医学 儿科医学 儿科医学
背景情况:
- 慢性病 (CKD) 显著影响年轻患者的口腔健康.
- 有限的数据存在于口臭发病率和牙科预防在这个人口中的影响.
- 这项研究调查了年轻CKD患者的口臭,这些患者接受了不同的口腔护理方案.
研究的目的:
- 探索患有慢性病的年轻患者口臭的患病率和特征.
- 评估密集口腔预防程序 (OPP) 与标准护理 (TAU) 对口臭的影响.
- 确定主要的挥发性硫化合物,这些化合物在这个人群中导致口臭.
主要方法:
- 30名年轻的CKD患者 (平均年龄14.2岁) 被纳入随机临床试验.
- 呼吸样本使用气相色谱分析了挥发性硫化合物 (VSCs).
- 评估了口腔卫生,舌头涂层和出血指数,以及患者和护理人员报告的口臭感知.
主要成果:
- 在密集口腔护理 (OPP) 和标准护理 (TAU) 组之间没有发现VSC水平的显著差异.
- 随着时间的推移,在OPP组中观察到减少二甲基硫化物和硫化的趋势.
- 在不同时间点在OPP和TAU组中都注意到了舌头涂层的显著减少,护理人员经常报告口臭.
结论:
- 年轻的CKD患者通常患有口臭,二甲基硫化物被确定为主要贡献者.
- 预防性牙科措施主要导致舌头涂层的减少,而不是显著减少VSCs.
- 需要进行进一步的研究,以开发儿童慢性病患者口臭的有效干预措施.
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