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儿科术后妄和区域大脑氧和之间的关联:一项前性观察性研究

Kexian Liu^1,2, Nan Lin^1,3, Ting Jin¹

¹Nursing Department, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, 310052, China.

|May 15, 2024

概括

区域大脑氧和 (rSO2) 与儿童手术后妄想症 (POD) 密切相关. 手术前后较低的rSO2水平预测POD,这表明NIRS监测可以帮助早期检测和干预.

科学领域:

儿科手术儿科手术
神经科学是一个神经科学.
关键护理医学关键护理医学

背景情况:

手术后痴呆症 (POD) 是儿科手术患者的常见并发症.
大脑缺血和降低区域大脑氧和度 (rSO2) 是对POD的假设贡献者.
了解rSO2-POD关系对于儿科外科护理至关重要.

研究的目的:

在接受手术的儿童中调查rSO2和POD之间的关联.
评估rSO2对儿科POD的预测和诊断价值.
探索大脑近红外光谱 (NIRS) 在监测rSO2对POD风险的有用性.

主要方法:

在儿童医院进行前性观察研究 (2020年11月 - 2021年3月).
大脑NIRS用于在儿科手术患者手术前和手术后测量rSO2.
使用DSM-5标准评估POD;统计分析包括t测试,等级总和测试和ROC曲线.

主要成果:

在211名儿童中,有61名 (28.9%) 患有POD.
患有POD的儿童呈现较低的手术前和术后最低rSO2,以及改变的平均rSO2变化.
对于各种rSO2参数 (AUC从0.649到0.717) 的ROC分析表明了良好的预测性能.

结论:

儿科POD和rSO2.2之间存在显著的关系.
rSO2测量,特别是使用NIRS,显示了作为小儿POD有效预测者的潜力.
监测rSO2可以促进儿童手术患者POD的早期识别和干预.

关键词:

狂妄症是什么意思狂妄症是什么意思儿科儿科儿科手术后的时间术后期区域大脑氧和区域大脑氧和

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