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Updated: Oct 2, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death

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在循环死亡后的捐赠中,在20分钟的无接触期后,心脏功能成功恢复:一个案例报告

Paolo Zanatta¹, Federico Linassi^1,2, Nicola Gasparetto³

¹Department of Anesthesiology and Critical Care, Treviso Regional Hospital AULSS 2 Marca Trevigiana, Treviso, Italy.

Transplantation

|May 16, 2024

概括

一个新的预先调节方案在停止维持生命治疗 (WLST) 和温暖缺血期间有效地保护了供体心脏,使得心脏的成功恢复和移植成为可能. 这种策略可以减轻器官损伤,提高捐赠者心脏的活力.

科学领域:

心脏病学心脏病学
移植医学移植医学
器官的保存器官的保存

背景情况:

在循环死亡确定 (DCD) 捐赠者中,停止维持生命治疗 (WLST) 会导致心脏骤停,限制心肌用于移植.
正热区域输液 (NRP) 或体外膜氧化 (ECMO) 有助于死后器官的优化.
需要进一步的策略来解决在WLST期间的应激反应和心肌复苏的缺血/再输损伤.

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