检查长期COVID和ME/CFS患者的福祉和认知功能,以及年龄相匹配的健康对照:一项案例对照研究
Nilihan E M Sanal-Hayes1, Marie Mclaughlin2, Lawrence D Hayes3
1School of Health and Society, University of Salford, Salford, UK; Sport and Physical Activity Research Institute, School of Health and Life Sciences, University of the West of Scotland, Glasgow, UK.
The American journal of medicine
|May 16, 2024
概括
长期COVID和肌痛性脑膜炎/慢性疲劳综合征 (ME/CFS) 患者经历了类似的福祉障碍,包括疼痛,疲劳和焦虑. 这些组和健康对照组之间的认知功能是可比的.
科学领域:
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 长期COVID和肌痛性脑膜炎/慢性疲劳综合征 (ME/CFS) 是具有重叠症状的衰弱性疾病.
- 以前的研究还没有直接比较这两组患者之间的幸福感和认知功能.
研究的目的:
- 将长期COVID和ME/CFS患者的福祉和认知功能与健康对照进行比较.
- 为了确定这些患者群体中损伤的特定领域.
主要方法:
- 使用移动应用程序进行远程数据收集.
- 通过验证的问卷 (例如,VAS,FSS,PSQI,EQ-5D,GAD-7,PHQ-9) 来评估幸福感.
- 使用SDMT,Stroop和Trails A/B等测试评估认知功能.
主要成果:
- 与对照人群相比,患有ME/CFS和长期COVID的个体在多个领域 (包括疼痛,疲劳,睡眠质量和焦虑) 报告了明显更糟糕的幸福感,包括疼痛,疲劳,睡眠质量和焦虑.
- 在长期COVID,ME/CFS和对照组之间没有观察到认知功能措施的显著差异.
- 长期COVID和ME/CFS组都表现出可比的自我报告幸福感损伤水平.
结论:
- 长期的COVID和ME/CFS表现出类似的健康损害模式.
- 改善福祉的有针对性的干预措施对于长期COVID和ME/CFS患者至关重要.
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