高水平的体力活动可以保护美国成年人患有抑郁症的全因死亡率
Yifei Wang1, Xin Yang1, Ying Zhou1
1College of Physical Education and Health, Guangxi Normal University, Guilin, Guangxi 541006, China.
Journal of affective disorders
|May 16, 2024
概括
参与高水平的体力活动 (PA) 在患有抑郁症的成年人中显著降低了全因死亡率 (ACM). 这一发现突显了PA在治疗抑郁症和改善寿命方面的重要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 临床研究 临床研究
背景情况:
- 众所周知,定期体育活动 (PA) 可以降低一般人群的全因死亡率 (ACM).
- 在被诊断患有抑郁症的个体中,PA对ACM的影响尚未得到充分证实.
- 这项研究调查了美国成年抑郁症患者的PA水平和ACM之间的关系.
研究的目的:
- 检查不同程度的体力活动与抑郁症成年患者全因死亡率之间的关联.
- 为身体活动在管理抑郁症患者健康结果中的作用提供证据.
主要方法:
- 利用了国家健康和营养检查调查 (2007-2018) 和死亡率数据的数据.
- 包括4850名美国成年人被诊断患有抑郁症的队列.
- 采用加权考克斯比例风险模型来分析PA水平 (MET-min/week) 和ACM,调整混因子.
主要成果:
- 在4850名参与者中,共发生503例死亡,平均随访时间为6.6年.
- 与没有PA相比,高水平的PA (>1200MET-min/week) 与ACM的风险明显较低 (HR=0.48).
- 高水平PA的这种保护作用在调整社会人口统计学和健康因素后仍然显著.
结论:
- 高水平的体力活动显示,对抑郁症成年患者全因死亡率的降低产生重大影响.
- 临床和公共卫生指南应纳入高水平PA对抑郁症患者的好处.
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