相关实验视频

Updated: May 3, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
11:24

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation

Published on: July 3, 2015

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质子闪光:剂量速率和分剂量对小鼠模型中的急性皮肤毒性的影响

Brita Singers Sørensen1, Eleni Kanouta2, Christina Ankjærgaard3

  • 1Danish Centre for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark; Department of Experimental Clinical Oncology, Aarhus University, Denmark; Department of Clinical Medicine, Health, AU; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.

International journal of radiation oncology, biology, physics
|May 16, 2024
PubMed
概括

闪光辐射疗法显示出正常组织节约效应. 这项研究发现,这种FLASH效应的剂量率因皮肤毒性水平而异,并且通过分剂量来减少.

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Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model06:21

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

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Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis07:08

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相关概念视频

Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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