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Updated: Jun 26, 2025

Observing and Quantifying Fibroblast-mediated Fibrin Gel Compaction
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纤维细胞对齐和矩阵重塑是由皮肤衍生的细胞外矩阵水凝中的刚度梯度引起的

Fenghua Zhao1, Meng Zhang2, Mehmet Nizamoglu3

  • 1University of Groningen, University Medical Centre Groningen, W.J. Kolff Institute for Biomedical Engineering and Materials Science-FB41, A. Deusinglaan 1, 9713 AV Groningen, the Netherlands; University of Groningen, University Medical Centre Groningen, Department of Biomaterials and Biomedical Technology-FB40, A. Deusinglaan 1, 9713 AV Groningen, the Netherlands; University of Groningen, University Medical Centre Groningen, Department of Pathology and Medical Biology, Hanzeplein 1 (EA11), 9713 GZ Groningen, the Netherlands.

Acta biomaterialia
|May 16, 2024
PubMed
概括

这项研究使用梯度刚性水凝创建了一种皮肤痕模型. 纤维细胞重塑基质,显示痕组织硬性如何影响细胞行为和愈合.

关键词:
原蛋白是一种原蛋白.细胞外基质水凝.纤维细胞细胞.梯度的刚性 梯度的刚性痕痕的 痕痕

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