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Updated: May 12, 2026

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood
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强大的CAR NK细胞的工程利用从极简DNA载体的非病毒性睡眠美女转换

Tobias Bexte1, Lacramioara Botezatu2, Csaba Miskey3

  • 1Goethe University, Department of Pediatrics, Experimental Immunology and Cell Therapy, Frankfurt am Main, Germany; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany; University Cancer Center (UCT) Frankfurt, Frankfurt, Germany; Mildred Scheel Career Center (MSNZ), Hospital of the Goethe University Frankfurt, Frankfurt, Germany; Institute for Transfusion Medicine and Immunohematology, German Red Cross Blood Service Baden-Württemberg - Hesse, Frankfurt, Germany.

Molecular therapy : the journal of the American Society of Gene Therapy
|May 16, 2024
PubMed
概括

这项研究引入了一种新型的非病毒方法,使用睡眠美女的转子来设计化学抗原受体 (CAR) 自然杀手 (NK) 细胞用于癌症免疫疗法,证明了增强的抗白血病疗效.

关键词:
汽车 汽车 汽车 汽车CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19 CD19在 NK 细胞中,NK 细胞是 NK 细胞.睡觉美女的睡眠美女急性淋巴细胞白血病急性淋巴细胞白血病一个全源的产物.非病毒性非病毒性.转换一个转换器.

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